Sunday , April 18 2021

Africans today save DNA from unknown extinct people


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(Caracas, April 26, EuropaPress). A study published in Genome Biology showed for the first time use artificial intelligence that African populations hybridize with other extinct people.

So far, it has been known that some missing populations, such as the Neanderthals or the Denizens, interfered with modern people outside of Africa. However, cross-bleeding was not repeatedly demonstrated in African populations.

Now, scientists led by David Comas, a researcher at the Institute of Evolutionary Biology (CSIC-Pompeu Fabra University) have identified the introgression of the extinct line of people in the DNA of today's African populations.

"This completely unknown archaic settlement, mixed with the ancestors of Africans and their genes, has been preserved in their genome so far," explains David Comas.

Belen Lorenté-Geldos, co-author of the study, explains: "The script we know in Africa of societies that mix in a complex way during its recent history is just the tip of the iceberg of the evolutionary history of people, and so will be complex from the very beginning. "

The researchers conducted a study of contemporary genomes from different populations with a wide range of life styles, languages ​​or geography on the African continent. By sequencing these current genomes, they showed that some of them came from introgression, as discussed in Geomagic Biology.

"Using tools for artificial intelligence and complete genomes, we managed to conclude the general history of the evolution of the African population," said Oscar Lao, researcher from the National Center for the Analysis of the Genome (CNAG-CRG), also one of the authors of the study.

"What surprised us is that to describe the genetic diversity that today is found in African populations, one must take into account the presence of the missing African archaic population, which would interfere with anatomical modern humans," he adds. This result shows that not only archaic populations were different from the sapiens' vines outside Africa (such as Neanderthals or Denisovani), but within this continent there were subpopulations with which the anatomically modern people who remained in Africa had offspring.

Through the use of tools for artificial intelligence and complete genomes, we succeeded round off the general history of the evolution of African populations.

"This discovery is questioning previous remarks about the transition of Neanderthals or Denizens to European or Asian ancestors because Africans have always been taken as a population model without introgression," explains David Comas. "Our research leads us to question some of the assumptions set out today based on the premise that the African population did not have introgression," he adds.

Belen Lorenté-Geldos concludes: "our method has allowed us to clearly reject the prevailing model which does not consider the archaic introgression in Africa.The new model we present, in addition, to check the amount of DNA in people of Eurasian Neanderthal origin, which could be up to three times what was previously estimated using previous models. "

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