Saturday , July 31 2021

Hormone "Can Reduce Chances of Spontaneous Abortion"

Baby NoahCopyright image
Samantha Allen

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Samantha Noah's son was born after participating in a large trial

Studies show that giving progesterone to hormones for women who have had a spontaneous abortion and experienced early bleeding in pregnancy could improve their chances of having a baby.

Researchers from Birmingham conducted an examination of 4,000 pregnant women.

Samantha Allen, 31, suffered a remark when she lost her first baby and then again during her second pregnancy.

After taking the hormone for eight weeks, she gave birth to her son Noah.

Progesterone is a hormone essential during pregnancy – to maintain the lining of the uterus where the embryo is implanted and to support the immune system.

Samantha was prescribed for a progesterone pig for the trial, which she took twice a day while she was pregnant for 16 weeks.

She said the bleeding stopped within a week from the commencement of the trial and pregnancy progressed very smoothly.

She now hopes that more women who have had miscarriage may benefit.

"I just hope they do not have to through the same pain – it takes its tax on you," she said.

The worsening affects one in five women, and vaginal bleeding in early pregnancy is associated with an increased risk of that happening.

With progesterone, which was already used in treatment with IVF, Samantha said she was not afraid to participate in the trial.

"I feel happy that I participated, I did not feel at risk, because it was not an early stage of the trial."

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Samantha Allen

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Samantha Allen with her husband and baby Noah

The study, published in the New England Journal of Medicine, included a group of about 2,000 pregnant women who received progesterone, while another group of the same number received a placebo or a doll.

All women experienced bleeding in early pregnancy.

Although the study showed that all women with early bleeding can not be helped with taking a hormone, the benefits are the highest in women with a history of recurrent abortions (three or more).

Among these women, there was a 15% increase in live birth rate – in 98 out of 137 women who had a baby, compared to 85 of 148 in the placebo group.

  • Baby joy for a woman left a "broken heart" from a hospital after a spontaneous abortion
  • "Opening the grief of miscarriage"

Arri Coomarasamy, a study leader and consultant gynecologist at the Birmingham Women's and Children's Hospital, said treatment could save thousands of babies.

"We hope this evidence will be examined by the National Institute of Health Care and Care and will be used to update national guidelines for women at risk of miscarriage," he said.

Currently, when women are potentially spontaneous, "there is nothing we can offer," he says.

But he said treatment would not work for all women who have abortion, as there were many complex reasons why a miscarriage occurs.

Only those women with progesterone-related problems can benefit, he added.

Jane Bruin, chief executive of the Tommy charity, said: "The results of this study are important for parents who have experienced miscarriage, they now have a stable and effective treatment option that will save many lives and will prevent much pain.

"It gives us confidence to believe that further research will bring more treatments and in the end will do much more abortions to prevent them."

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