Sunday , April 11 2021

Insomnia may affect the "good" cholesterol – Health> News

A new study explains why insufficient rest increases the risk of heart disease. Researchers have shown that sleep deficiency can have a negative impact on the level of cholesterol.

A study recently published in Finland found that too little sleep could change the genes that balance the cholesterol level in the body. Thus, people who wake at night or suffer from insomnia may have a lower HDL-type "good" than those who sleep at the recommended 7-8 hour range.

HDL cholesterol allows the removal of LDL "bad" cholesterol particles from the arteries. "Bad" cholesterol exacerbates the risk of atherosclerosis, which is a slight accumulation of the walls of the arteries and endangers the health of the heart, favoring a heart attack and stroke. Under these conditions, it is very important that you have a normal HDL cholesterol level to ensure that your heart's functions are optimally achieved.

The team of researchers came to the conclusions mentioned by carrying out a thorough epidemiological analysis. In this experiment, 21 participants were studied, who slept under laboratory conditions for 5 nights. The duration of sleep for 14 participants was limited to 4 hours, while the rest slept on the ideal range of 7-8 hours.

Lack of sleep has reduced the activity of cholesterol-regulating genes

During 5 days, the analyzes were collected from all participants, and scientists analyzed the level of cholesterol and the way the genes acted to balance it. Compared to those who slept enough, those who did not rest only 4 hours at night had much less activity on the cholesterol coding genes.

Next, 2,739 participants were interviewed, who filled in the questionnaires in which it was necessary to determine how many slept each night. Those who said they slept very little were included in the main study category to determine the effects on cholesterol. The control of the said duration was also performed, comparing the duration considered sufficient for the participants to feel the rest and real needs of the body.

The lower level of HDL cholesterol among people who sleep very little

At the moment when the samples were taken from all the participants, it was again revealed that the cholesterol-coding genes had decreased activity in those who slept less.

In addition, participants with sleep deprivation problems also had a low level of HDL-cholesterol particles. The team of researchers is of the opinion that the sleep analysis of 5 nights in laboratory conditions and large-scale epidemiological studies show that insufficient rest, even for a short period of time, can have a significant negative impact on the body. This can explain why people suffering from insomnia or other sleep disorders are more often diagnosed with heart disease.

"Our study showed that one day of sleep does not change the response of the immune system and the metabolic function in a negative way. Our next goal is to determine how small the difference between normal sleep and insufficient rest should be to see these changes", says Dr. Wilma Aho, author of the study, a syngologist at the University of Helsinki.

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