Juan Foyth's headline was the sixth loss of the same title, and after encouraging to appear against Arsenal and Chelsea, they were probably unfortunate against Spurs.
Jordan Ayew essentially gave Foyth an award when Spurs looked unlikely, and Alexander Sorloth threatened to level off.
After the Manchester United football break, Manchester United will face Manchester before their matches are better, and Van Aanholt said on the club's official website: "We played well, we played hard, but we did not score any points, it's frustrating, but we have to stay together .
"It's a difficult time, but as I said, we have to stay together as always and the points will come.
"We were solidly defensive, it was just a bad day.
"We've been here before, but as I said, we're very good, we just have to score points, and as soon as we get points, everything will be fine.
Spurs made many changes to the team that defeated PSV Eindhoven 2-1 on Tuesday, reminiscent of Foyth, Kieran Trippier, Victor Wanyama, Moussa Sissoko and Erik Lamela, and despite the lack of their normal intensity, their manager Mauricio Pochettino praised the power of his team.
Trippier was also replaced by Serge Aurier in the first half after injury, and Pochettino said: "Team is the most important, faith, players. The most important thing is that all players are competitive.
"I like it the most, I congratulate all of them because the effort was huge and all the employees did a fantastic job, I want to congratulate them all, I'm so happy, so happy."