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Measles makes them susceptible to further disease – Infection erases immune memory



Measles is not a harmless childhood disease. At worst, the infection can be fatal. That is so familiar. But researchers at the Paul Ehrlich Institute (PEI), in collaboration with researchers from the UK and the Netherlands, have now discovered that measles viruses have erased some of their immune memory over the years.

This means that affected people are more susceptible to infections with other pathogens after surviving the disease.

In Germany, vaccination against measles is mandatory by 2020. Then children, students and certain adults Kita should prove that they are vaccinated. Not without reason – because infections are increasing, although measles should have been eradicated long ago.

For example, the European Center for Disease Prevention and Control (ECDC) is talking about the recurrence of measles in Europe. Accordingly, five countries, including Germany, where transmissions are still endemic – ie. within the population – are responsible for that.

Measles can be fatal

Measles infections can be fatal in severe cases. In addition, the virus weakens the patient's immune system to other pathogens. Thus, in the case of measles infection more often other infections such as bacterial infections of the lungs or middle ear.

In addition, a study of a smallpox group in the United Kingdom (UK) found that ten to fifteen percent of sick children still had signs of a severe immune system disorder five years after the measles infection. This in turn led to an increased incidence of further infections.

The measles vaccine also protects against other infectious diseases

Measles is nothing but a cause for parties. "The vaccine against chickenpox is not only important for protecting against measles viruses, but it also protects against the emergence or serious progression of other infectious diseases," said Professor Klaus Fikutek, president of the Paul Erlich Institute. It protects immune memory, which can be severely impaired during measles infections.

According to the Paul Ehrlich Institute, the results now confirm that the immune system after measles infection has virtually forgotten what pathogens it had previously come into contact with.

To this end, the animals (ferrites) were initially immunized against the flu (flu) and some animals infected with the mutant hunter-gatherer dispersal virus, which is linked to the measles virus. Dogs infected with the Distinguished Canine Virus are reported to have lost a lot of influenza antibodies and had a heavier disease course compared to animals that were not infected when later infected with the influenza virus.

IN THE VIDEO Everything you need to know about measles


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