Thursday , January 21 2021

Studies show that bariatric surgery may reduce the severity of Covid-19 in obese patients – health



A study by the Cleveland Clinic found that in obese patients who tested positive for Covid-19, a previous history of bariatric surgery was significantly associated with a lower risk of admission to a hospital and intensive care unit.

The results were published in the journal Surgery for Obesity and Related Diseases.

In recent months, researchers around the world have identified obesity as a risk factor for developing severe Covid-19, which may require hospitalization, intensive care, and the use of ventilator support. The Centers for Disease Control and Prevention reports that more than 70% of adults in the United States are overweight or obese, which may increase the risk of severe coronavirus disease.

Obesity is a complex disease caused by several factors that weaken the immune system. Obesity creates a chronic inflammatory condition that causes overproduction of cytokines, which are small proteins involved in the immune response.

“Coronavirus infection also activates the immune system to release cytokines, which can lead to overproduction of cytokines that damage organs.” “It may partly explain the severity of the infection in obese patients,” said Ali Aminian, PhD, director of the Cleveland Clinic’s Bariatric and Metabolic Institute and lead researcher.

In addition, obesity increases the risk of cardiovascular disease, hypertension, diabetes, kidney disease, and thrombus formation. These conditions can lead to poor outcomes after infection with SARS-KOV-2, a virus that causes Covid-19. Obesity can also affect the respiratory system. Many obese patients have underlying lung conditions, such as sleep apnea and obese hypoventilation syndrome, which may worsen the results of Covid-19 pneumonia.

“Dr. The Aminian study provides further evidence for an important link between obesity and poor coronavirus infection outcomes. “The study shows for the first time that significant weight loss through bariatric surgery can really reduce the risk of serious disease in these patients.” Clinic

Looking at 4,365 patients who tested positive for SARS-CoV-2 between March 8, 2020, and July 22, 2020, the researchers identified 33 patients with a history of weight loss surgery (20 patients had sleeve gastrectomy and 13 patients had gastric bypass). Roux-en-Y). The 33 surgical patients were carefully matched from 1:10 of obese non-surgical patients to collect a group of 330 control patients with a body mass index of 40 or more at the time of SARS-CoV-2 testing.

This cohort study of 363 patients found that persistent weight loss and improvement in diabetes and hypertension in the bariatric surgery group prior to infection with Covid-19 was associated with a much lower hospital admission rate and ICU.

Eighteen percent of patients in the weight loss surgery group and 42% of patients in the control group sought hospitalization in agreement with Covid-19. In addition, 13% of patients in the control group sought ICU admission, 7% required mechanical ventilation. , and 2.4% died. None of them happened in the surgical group.

“Patients after bariatric surgery become significantly healthier and can better fight the virus,” adds Dr Aminian. “If confirmed by future studies, this can be added to the long list of health benefits of bariatric surgery, such as improving diabetes, hypertension, fatty liver disease, sleep apnea and preventing heart attack, stroke, kidney disease and death. “

Another study by the Cleveland Clinic found that weight loss surgery was associated with a 40% reduction in the risk of death and heart complications in patients with diabetes and obesity.

(This story was published by a wiring agency feed without any changes to the text.)

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