A team of researchers led by scientists at the University of New York's Medical School identified molecular signaling pathways that prevent hair growth from wounded skin, which can help in the search for better drugs to restore baldness, as well as Gene reported.
In the study, scientists activated the signal path of the sonic hedgehog (Shh) that use cells to communicate with each other. It is known that the pathway is very active during the early stages of human growth in the uterus, when the hair follicles form, but stagnate in the injured skin in healthy adults.
"We have identified that the activation of the Shh path restores a regenerative dermal niche, called the dermal papilla, which is necessary and sufficient for the neocolonium of the hair follicles (HFN)," the authors wrote in their work.
"Our results show that the stimulation of fibroblasts through the path of the sonic hedgehog can trigger the growth of the hair, which has not previously been observed in wound healing," said study lead author Mayiye Ito, MD. professor of the Dermatology Department at the Health Care Center chain associated with the University of New York.
The researcher said she hoped that the job would help her achieve her main goal, and that it is mature skin to return to her embryonic state, so that she can produce new hair follicles, not only in the event of injuries, but also in people who remained bald with aging.