A group of scientists from the University of California, USA, have identified the mechanism by which carcinogens absorbed glucose and attracted energy to survive and tumor growth.
At the same time, the content of a particular molecule makes it possible to detect a precancerous condition that causes the cells to grow, writes the online edition of MedicalXpress.
Experts have found that the protein used in the treatment of type 2 diabetes mellitus plays an important role in the formation of new tumor formations. According to their data, the sodium glucose co-transporter 2 (SGLT2), which is responsible for the transmission of glucose in the cell, is one of the main providers of "food" for cancer cells.
Cancer cells need glucose to survive and grow. Therefore, they need a multitude of transport proteins, glucose transporters.
Previous studies have shown that SGLT2 can play a major role in the development of some types of cancer, including cancer of the pancreas and the prostate.
Using positron emission tomography, the researchers determined the activity of various glucose transporters in cancer cells at different stages of their development. Thus, they found that these cells contain a large amount of SGLT2. According to scientists, this suggests that new tumors provide carbohydrates mainly via SGLT2, and not through glucose transporters.
By reviewing their data, the researchers found that the increase in SGLT2 may occur before a tumor develops, making this specific protein a marker for early detection of the disease.
The discovery of American scientists could have had an impact on early cancer prevention methods.