Saturday , July 31 2021

Knowledge of ancestors can be a solution to bacterial resistance



When the world is on a red warning, because we risk (unfortunately, without users to understand the dangers) to leak antibiotics, it seems that in 2019 it started with the right foot – or with the top, at least – in what for public health. Today's picture is this: antibiotic-resistant superbiotics could only kill 1.3 million people in Europe until 2050, according to recent surveys, and for the World Health Organization, the lack of antibiotics to combat them is "One of the biggest threats to the global health, food safety and current development ".

The good news comes from Wales, United Kingdom: a team from the Swansea University School of Medicine, consisting of researchers from Wales, Brazil, Iraq and Northern Ireland, discovered a new type of bacteria – called Streptomyces sp. mythophore – capable of inhibiting the growth of multiresistant pathogens. And he found it, incredibly, in mud.

The land of the druids

The land they analyzed is located in Fermanagh, Northern Ireland, known as Boho Highlands and is said to have healing properties. It does not seem accidental that the area was occupied by the druids, 1,500 years ago, and before the Neolithic 4,000 years ago.

One of the team members, Gary Quinn, a former Boho resident, was aware that, traditionally, a small amount of soil was wrapped in a cloth and was used to treat toothache and throat and neck infections.

It is also no coincidence that researchers give verification of legends: the search for replacement of antibiotics to combat multiple resistance has led researchers to explore new sources, including popular drugs: a field of studies known as ethnopharmacology.

Enemies

In this reliable possible fight of "bacteria versus bacteria", the bad ones from the film are, precisely, some identified by the WHO as responsible for the most serious infections related to medical attention.

"This new type of bacteria is effective against the four (vancomycin resistant encecoccus fusion, Staphylococcus aureus, Klebsiella pneumonia and Vancomycin resistant carbinepenem-resistant Acinetobacter baumanii) of the six major pathogens that are resistant to antibiotics. Our discovery is an important step forward in the fight against resistance to antibiotics, "he said. Paul Dyson, from the Faculty of Medicine at Swansea University. "Our results show that it is worth investigating folklore and traditional drugs in the search for new antibiotics. Scientists, historians and archeologists may have something to contribute to this task. It seems that part of the answer to this very modern problem can be in the wisdom of past, "he added.

But we must be clear: for now, it is only hope, because it is still not clear – although the team is already investigating – which component of the new species prevents the growth of pathogens.

"It takes a molecule that generates an antibacterial effect to be very different from those developed up to now to fight resistance. Bacteria are very smart to survive and they do not win by quickly creating mechanisms that deactivate antibiotics," LA GASETA, an infectious disease Tucuman. Monica Herbst. "The bacteria is isolated, but there is a long way to learn to produce a new antibiotic, and later, experimenting with animals and clinical trials in humans. And it should also be interested in the pharmaceutical industry because it has to make a huge investment in development of a new drug, "he added.


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